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inverted phase contrast microscope  (Nikon)


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    Structured Review

    Nikon inverted phase contrast microscope
    Inverted Phase Contrast Microscope, supplied by Nikon, used in various techniques. Bioz Stars score: 99/100, based on 14722 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/inverted+phase-contrast+microscope/Inverted+Microscopes/pmc12963817-204-50-56
    Average 99 stars, based on 14722 article reviews
    inverted phase contrast microscope - by Bioz Stars, 2026-09
    99/100 stars

    Images

    Related Articles

    Infection:

    Article Title: Ex vivo enhancement of CD8+ T cell activity using functionalized hydrogel encapsulating tonsil-derived lymphatic endothelial cells
    Article Snippet: The changes in cell morphologies were analyzed during induced differentiation of TMSCs to T-LECs at passage 3 using an inverted phase-contrast microscope (Nikon, Japan).

    Article Title: Effects of calcium oxalate crystals on neutrophil cellular proteome and functions: implications for nephrolithiasis.
    Article Snippet: The (adherent) macrophages were then imaged under the Nikon Eclipse Ti-S inverted phasecontrast microscope.

    Article Title: Targeted protein degradation of PDE4 shortforms by a novel proteolysis targeting chimera
    Article Snippet: The spheroids were visualized on an inverted phase‐contrast microscope with 4x magnification (Nikon Eclipse Ts2), and images were obtained with the DS‐Fi3 camera and captured through NIS Elements (Nikon) on day 0 (before treatment start) and every 3–4 days after treatments.

    Article Title: Single-cell transcriptome analysis of stem cells from human exfoliated deciduous teeth investigating functional heterogeneity in immunomodulation
    Article Snippet: The culture medium was replaced every 3 days, and the cells were observed every 24 h using an inverted phase‐contrast microscope, magnification, × 10 (Nikon).

    Article Title: Phytol and bilimbi phytocompounds induce thermogenic adipocyte differentiation: An in vitro study on potential anti-obesity effects
    Article Snippet: Morphological changes and intracellular lipid droplets were observed under an inverted phase-contrast microscope and the images were captured using Nikon.

    Article Title: Horizontal and vertical transmission of covert mortality nodavirus in the marine fish
    Article Snippet: Covert mortality nodavirus (CMNV) is a vital emerging virus in aquaculture issued by World Organization for Animal Health recently.. It can infect teleost fish, but the mode of transmission remains unclear.. Therefore, this study investigated the potential of vertical and horizontal transmission of CMNV in marine fish using the marine model organism of marine medaka Oryzias melastigma.

    Article Title: Effects of calcium oxalate crystals on neutrophil cellular proteome and functions: implications for nephrolithiasis
    Article Snippet: The (adherent) macrophages were then imaged under the Nikon Eclipse Ti-S inverted phase-contrast microscope.

    Article Title: Biofabrication of HepG2 Cells-Laden 3D Structures Using Nanocellulose-Reinforced Gelatin-Based Hydrogel Bioinks: Materials Characterization, Cell Viability Assessment, and Metabolomic Analysis.
    Article Snippet: The successful replication of the intricate architecture of human tissues remains a major challenge in the biomedical area.. Three-dimensional (3D) bioprinting has emerged as a promising approach for the biofabrication of living tissue analogues, taking advantage of the use of adequate bioinks and printing methodologies.. Here, a hydrogel bioink based on gelatin (Gel) and nanofibrillated cellulose (NFC), cross-linked with genipin, was developed for the 3D extrusion-based bioprinting of hepatocarcinoma cells (HepG2).

    Microscopy:

    Article Title: Ex vivo enhancement of CD8+ T cell activity using functionalized hydrogel encapsulating tonsil-derived lymphatic endothelial cells
    Article Snippet: The changes in cell morphologies were analyzed during induced differentiation of TMSCs to T-LECs at passage 3 using an inverted phase-contrast microscope (Nikon, Japan).

    Article Title: Effects of calcium oxalate crystals on neutrophil cellular proteome and functions: implications for nephrolithiasis.
    Article Snippet: The (adherent) macrophages were then imaged under the Nikon Eclipse Ti-S inverted phasecontrast microscope.

    Article Title: Targeted protein degradation of PDE4 shortforms by a novel proteolysis targeting chimera
    Article Snippet: The spheroids were visualized on an inverted phase‐contrast microscope with 4x magnification (Nikon Eclipse Ts2), and images were obtained with the DS‐Fi3 camera and captured through NIS Elements (Nikon) on day 0 (before treatment start) and every 3–4 days after treatments.

    Article Title: Single-cell transcriptome analysis of stem cells from human exfoliated deciduous teeth investigating functional heterogeneity in immunomodulation
    Article Snippet: The culture medium was replaced every 3 days, and the cells were observed every 24 h using an inverted phase‐contrast microscope, magnification, × 10 (Nikon).

    Article Title: Phytol and bilimbi phytocompounds induce thermogenic adipocyte differentiation: An in vitro study on potential anti-obesity effects
    Article Snippet: Morphological changes and intracellular lipid droplets were observed under an inverted phase-contrast microscope and the images were captured using Nikon.

    Article Title: Horizontal and vertical transmission of covert mortality nodavirus in the marine fish
    Article Snippet: Covert mortality nodavirus (CMNV) is a vital emerging virus in aquaculture issued by World Organization for Animal Health recently.. It can infect teleost fish, but the mode of transmission remains unclear.. Therefore, this study investigated the potential of vertical and horizontal transmission of CMNV in marine fish using the marine model organism of marine medaka Oryzias melastigma.

    Article Title: Effects of calcium oxalate crystals on neutrophil cellular proteome and functions: implications for nephrolithiasis
    Article Snippet: The (adherent) macrophages were then imaged under the Nikon Eclipse Ti-S inverted phase-contrast microscope.

    Article Title: Biofabrication of HepG2 Cells-Laden 3D Structures Using Nanocellulose-Reinforced Gelatin-Based Hydrogel Bioinks: Materials Characterization, Cell Viability Assessment, and Metabolomic Analysis.
    Article Snippet: The successful replication of the intricate architecture of human tissues remains a major challenge in the biomedical area.. Three-dimensional (3D) bioprinting has emerged as a promising approach for the biofabrication of living tissue analogues, taking advantage of the use of adequate bioinks and printing methodologies.. Here, a hydrogel bioink based on gelatin (Gel) and nanofibrillated cellulose (NFC), cross-linked with genipin, was developed for the 3D extrusion-based bioprinting of hepatocarcinoma cells (HepG2).



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    Alizarin Red S staining and ARS quantification of mineralized matrix in DPSCs cultured under different conditions for 7 and 14 days. a Representative images show calcium deposition in DPSCs cultured in osteogenic differentiation medium (ODM) alone (control), ODM supplemented with a low dose of Metformin (500 µM), or a high dose of Metformin (1000 µM). The magnification is 20×, and the scale bar is 50 μm. Images were captured using the LABOMED Trinocular inverted phase contrast microscope model <t>TCM400</t> and Atlas 16MP CMOS USB Camera with PixelPro 3.0 software (LABOMED, USA). b Bar graphs show ARS concentrations representing mineral deposition at days 7 and 14. Error bars represent standard deviations. Statistical significance was assessed using one-way ANOVA followed by Tukey’s post-hoc test (a: vs. ODM; b: vs. low dose of Metformin; c: vs. high dose of Metformin. Abbreviations: DPSCs: Dental pulp-derived mesenchymal stem cells, ODM: Osteogenic differentiation medium, MET: Metformin, ARS: Alizarin red stain
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    Alizarin Red S staining and ARS quantification of mineralized matrix in DPSCs cultured under different conditions for 7 and 14 days. a Representative images show calcium deposition in DPSCs cultured in osteogenic differentiation medium (ODM) alone (control), ODM supplemented with a low dose of Metformin (500 µM), or a high dose of Metformin (1000 µM). The magnification is 20×, and the scale bar is 50 μm. Images were captured using the LABOMED Trinocular inverted phase contrast microscope model <t>TCM400</t> and Atlas 16MP CMOS USB Camera with PixelPro 3.0 software (LABOMED, USA). b Bar graphs show ARS concentrations representing mineral deposition at days 7 and 14. Error bars represent standard deviations. Statistical significance was assessed using one-way ANOVA followed by Tukey’s post-hoc test (a: vs. ODM; b: vs. low dose of Metformin; c: vs. high dose of Metformin. Abbreviations: DPSCs: Dental pulp-derived mesenchymal stem cells, ODM: Osteogenic differentiation medium, MET: Metformin, ARS: Alizarin red stain
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    Alizarin Red S staining and ARS quantification of mineralized matrix in DPSCs cultured under different conditions for 7 and 14 days. a Representative images show calcium deposition in DPSCs cultured in osteogenic differentiation medium (ODM) alone (control), ODM supplemented with a low dose of Metformin (500 µM), or a high dose of Metformin (1000 µM). The magnification is 20×, and the scale bar is 50 μm. Images were captured using the LABOMED Trinocular inverted phase contrast microscope model <t>TCM400</t> and Atlas 16MP CMOS USB Camera with PixelPro 3.0 software (LABOMED, USA). b Bar graphs show ARS concentrations representing mineral deposition at days 7 and 14. Error bars represent standard deviations. Statistical significance was assessed using one-way ANOVA followed by Tukey’s post-hoc test (a: vs. ODM; b: vs. low dose of Metformin; c: vs. high dose of Metformin. Abbreviations: DPSCs: Dental pulp-derived mesenchymal stem cells, ODM: Osteogenic differentiation medium, MET: Metformin, ARS: Alizarin red stain
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    Alizarin Red S staining and ARS quantification of mineralized matrix in DPSCs cultured under different conditions for 7 and 14 days. a Representative images show calcium deposition in DPSCs cultured in osteogenic differentiation medium (ODM) alone (control), ODM supplemented with a low dose of Metformin (500 µM), or a high dose of Metformin (1000 µM). The magnification is 20×, and the scale bar is 50 μm. Images were captured using the LABOMED Trinocular inverted phase contrast microscope model <t>TCM400</t> and Atlas 16MP CMOS USB Camera with PixelPro 3.0 software (LABOMED, USA). b Bar graphs show ARS concentrations representing mineral deposition at days 7 and 14. Error bars represent standard deviations. Statistical significance was assessed using one-way ANOVA followed by Tukey’s post-hoc test (a: vs. ODM; b: vs. low dose of Metformin; c: vs. high dose of Metformin. Abbreviations: DPSCs: Dental pulp-derived mesenchymal stem cells, ODM: Osteogenic differentiation medium, MET: Metformin, ARS: Alizarin red stain
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    Image Search Results


    Alizarin Red S staining and ARS quantification of mineralized matrix in DPSCs cultured under different conditions for 7 and 14 days. a Representative images show calcium deposition in DPSCs cultured in osteogenic differentiation medium (ODM) alone (control), ODM supplemented with a low dose of Metformin (500 µM), or a high dose of Metformin (1000 µM). The magnification is 20×, and the scale bar is 50 μm. Images were captured using the LABOMED Trinocular inverted phase contrast microscope model TCM400 and Atlas 16MP CMOS USB Camera with PixelPro 3.0 software (LABOMED, USA). b Bar graphs show ARS concentrations representing mineral deposition at days 7 and 14. Error bars represent standard deviations. Statistical significance was assessed using one-way ANOVA followed by Tukey’s post-hoc test (a: vs. ODM; b: vs. low dose of Metformin; c: vs. high dose of Metformin. Abbreviations: DPSCs: Dental pulp-derived mesenchymal stem cells, ODM: Osteogenic differentiation medium, MET: Metformin, ARS: Alizarin red stain

    Journal: BMC Oral Health

    Article Title: Dose-dependent effects of Metformin on proliferation and odontogenic differentiation of dental pulp stem cells

    doi: 10.1186/s12903-026-08221-w

    Figure Lengend Snippet: Alizarin Red S staining and ARS quantification of mineralized matrix in DPSCs cultured under different conditions for 7 and 14 days. a Representative images show calcium deposition in DPSCs cultured in osteogenic differentiation medium (ODM) alone (control), ODM supplemented with a low dose of Metformin (500 µM), or a high dose of Metformin (1000 µM). The magnification is 20×, and the scale bar is 50 μm. Images were captured using the LABOMED Trinocular inverted phase contrast microscope model TCM400 and Atlas 16MP CMOS USB Camera with PixelPro 3.0 software (LABOMED, USA). b Bar graphs show ARS concentrations representing mineral deposition at days 7 and 14. Error bars represent standard deviations. Statistical significance was assessed using one-way ANOVA followed by Tukey’s post-hoc test (a: vs. ODM; b: vs. low dose of Metformin; c: vs. high dose of Metformin. Abbreviations: DPSCs: Dental pulp-derived mesenchymal stem cells, ODM: Osteogenic differentiation medium, MET: Metformin, ARS: Alizarin red stain

    Article Snippet: Images were captured using the LABOMED Trinocular inverted phase contrast microscope model TCM400 and Atlas 16MP CMOS USB Camera with PixelPro 3.0 software (LABOMED, USA). b Bar graphs show ARS concentrations representing mineral deposition at days 7 and 14.

    Techniques: Staining, Cell Culture, Control, Microscopy, Software, Derivative Assay